...I think will stick with 3.5E for the most part. I will probably do some house-ruling to streamline stuff, modify classes, and take the best of Saga Edition and will be rebuilding monsters and spellcasting to fit the setting better. But everything will be doable within the 3.5E framework (and, I expect, work within E-Tools, which is a bonus).
More details as I work them out.
jamesbarrett, sirfox, laurie_robey, and hantamouse, if you have any particular issues w/ 3.5E you'd like to see addressed, please let me know. Also, do you have a preference as to whether we adopt the Condition Track from Saga Edition?